All posts by Mark H

About Mark H

Information technologist, knowledge management expert, and writer. Academic background in knowledge management, social and natural sciences, information technologies, learning, educational technologies, and philosophy. Married with one adult child who's married and has a teenage daughter.

Book review – Life 3.0: Being Human in the Age of Artificial Intelligence, by Max Tegmark

Max Tegmark’s new book, Life 3.0: Being Human in the Age of Artificial Intelligence, introduces a framework for defining types of life based on the degree of design control that sensing, self-replicating entities have over their own ‘hardware’ (physical forms) and ‘software’ (“all the algorithms and knowledge that you use to process the information from your senses and decide what to do”).

It’s a relatively non-academic read and well worth the effort for anyone interested in the potential to design the next major forms of ‘Life’ to transcend many of the physical and cognitive constraints that have us now on the brink of self-destruction. Tegmark’s forecast is optimistic.

Wild systems theory (WST) – context and relationships make reality meaningful

Edward has posted some great thoughts and resources on embodied cognition (EC). I stumbled on some interesting information on a line of thinking within the EC literature. I find contextualist, connectivist approaches compelling in their ability to address complex-systems such as life and (possibly) consciousness. Wild systems theory (WST) “conceptualizes organisms as multi-scale self-sustaining embodiments of the phylogenetic, cultural, social, and developmental contexts in which they emerged and in which they sustain themselves. Such self-sustaining embodiments of context are naturally and necessarily about the multi-scale contexts they embody. As a result, meaning (i.e., content) is constitutive of what they are. This approach to content overcomes the computationalist need for representation while simultaneously satisfying the ecological penchant for multi-scale contingent interactions.”While I find WST fascinating, I’m unclear on whether it has been or can be assessed empirically. What do you think? Is WST shackled to philosophy?

Can one person know another’s mental state? Physicalists focus on how each of us develops a theory of mind (TOM) about each of the other people we observe. TOM is a theory because it is based on assumptions we make about others’ mental states by observing their behaviors. It is not based on any direct reading or measurement of internal processes. In its extreme, the physicalist view asserts that subjective experience and consciousness itself are merely emergent epiphenomena and not fundamentally real.

EC theorists often describe emergent or epiphenomenal subjective properties such as emotions and conscious experiences as “in terms of complex, multi-scale, causal dynamics among objective phenomena such as neurons, brains, bodies, and worlds.” Emotions, experiences, and meanings are seen to emerge from, be caused by or identical with, or be informational aspects of objective phenomena. Further, many EC proponents regards subjective properties as “logically unnecessary to the scientific description.” Some EC theorists conceive of the non-epiphenomenal reality of experience in a complex systems framework and define experience in terms of relational properties. In Gibson’s (1966) concept of affordances, organisms perceive behavioral possibilities in other organisms and in their environment. An affordance is a perceived relationship (often in terms of utility), such a how an organism might use something–say a potential mate, prey/food, or a tool. Meaning arises from “bi-directional aboutness” between an organism and what it perceives or interacts with. Meaning is about relationship.

(A very good, easy read on meaning arising from relationships is the book Learning How to Learn, by Novak and Gowin. In short, it’s the connecting/relating words such as is, contains, produces, consumes, etc., that enable meaningful concepts to be created in minds via language that clarifies context.)

Affordances and relationality at one level of organization and analysis carve out a non-epiphenomenal beachhead but do not banish epiphenomena from that or other levels. There’s a consideration of intrinsic, non-relational properties (perhaps mass) versus relational properties (such as weight). But again, level/scale of analysis matters (“mass emerges from a particle’s interaction with the Higgs field” and is thus relational after all) and some take this line of thinking to a logical end where there is no fundamental reality.

In WST, “all properties are constituted of and by their relations with context. As a result, all properties are inherently meaningful because they are naturally and necessarily about the contexts within which they persist. From this perspective, meaning is ubiquitous. In short, reality is inherently meaningful.”

2. Jordan, J. S., Cialdella, V. T., Dayer, A., Langley, M. D., & Stillman, Z. (2017). Wild Bodies Don’t Need to Perceive, Detect, Capture, or Create Meaning: They ARE Meaning. Frontiers in psychology8, 1149. Available from: [accessed Nov 09 2017]

BMAI members repository copy (PDF):

Your brain on AI-powered, immersive, virtual reality social networks

Kevin Kelly, the founder of Wired Magazine, forecasts virtual reality (VR) becoming our primary social environment within five years. VR experiences will be increasingly interactive (physically and socially). Our brains will process VR sensations as real.

The price of this novelty is all your data, historical and biometric, and with that will come more advertising than ever. What is the beginning of a new dimension of fun, will be the end of privacy.

AI more advanced than what keeps people addicted to current social media and search platforms will attract and keep social VR participants. How will personal and group cognition and behavior change when VR becomes more compelling than ‘legacy reality?’

See Kelly’s 5-minute talk at

Sex differences in the gut-microbiome-brain axis


In recent years, the bidirectional communication between the gut microbiome and the brain has emerged as a factor that influences immunity, metabolism, neurodevelopment and behaviour. Cross-talk between the gut and brain begins early in life immediately following the transition from a sterile in utero environment to one that is exposed to a changing and complex microbial milieu over a lifetime. Once established, communication between the gut and brain integrates information from the autonomic and enteric nervous systems, neuroendocrine and neuroimmune signals, and peripheral immune and metabolic signals. Importantly, the composition and functional potential of the gut microbiome undergoes many transitions that parallel dynamic periods of brain development and maturation for which distinct sex differences have been identified. Here, we discuss the sexually dimorphic development, maturation and maintenance of the gut microbiome–brain axis, and the sex differences therein important in disease risk and resilience throughout the lifespan.

Promising metabolic therapy for dementias

An article describes a personalized therapeutic program involving 10 patients and using multiple modalities for metabolic enhancement for neurodegeneration (MEND).

The first 10 patients who have utilized this program include patients with memory loss associated with Alzheimer’s disease (AD), amnestic mild cognitive impairment (aMCI), or subjective cognitive impairment (SCI). Nine of the 10 displayed subjective or objective improvement in cognition beginning within 3-6 months, with the one failure being a patient with very late stage AD. Six of the patients had had to discontinue working or were struggling with their jobs at the time of presentation, and all were able to return to work or continue working with improved performance. Improvements have been sustained, and at this time the longest patient follow-up is two and one-half years from initial treatment, with sustained and marked improvement. These results suggest that a larger, more extensive trial of this therapeutic program is warranted. The results also suggest that, at least early in the course, cognitive decline may be driven in large part by metabolic processes. Furthermore, given the failure of monotherapeutics in AD to date, the results raise the possibility that such a therapeutic system may be useful as a platform on which drugs that would fail as monotherapeutics may succeed as key components of a therapeutic system.

Cognitive decline as early as 18 years prior to clinical diagnosis of dementia

Performance on individual cognitive tests of episodic memory, executive function, and global cognition also significantly predicted the development of AD dementia, with associations exhibiting a similar trend over 18 years.

Conclusions: Our findings suggest that cognitive impairment may manifest in the preclinical phase of AD dementia substantially earlier than previously established.

Deep clustering machine learning enables AI to distinguish individual voices in a crowd

AI system can isolate individuals’ voices from other environmental noise, including other voices. Such a system has many potential uses, both benign and nefarious. The ability is rapidly improving to untangle signals from noise and identify which signals are from which sources. The approach should be able to apply to other kinds of signals too, not only sounds.

Neuroscience of Empathy

(This is copied from the Meetup site. Thanks again to Brent for hosting.)


Empathy is the ability to put yourself in another person’s shoes and understand how they feel- to be them, even for a second. It’s the link between self and others: how we connect, heal, and relate. Considering its importance in every aspect of our lives, we are taking a deeper look at the neuroscience behind empathy.

Recommended Preparation Info.

The Neuroscience of Empathy | Article | 5 minutes (

The Neuroscience of Compassion | Video | 20 min (

Jeremy Rifkin: The empathic civilization | Video | 10 min (


Empathy for others’ pain rooted in cognition rather than sensation | Article | 5 min (

Thomas Lewis: “The Neuroscience of Empathy” | Video | 60 min (

Suggested Additional Info.

Feeling Others’ Pain: Transforming Empathy into Compassion | Article | 5 min (

Structural basis of empathy and the domain general region in the anterior insular cortex | Study | 20 min (

Neurobiology of Empathy and Callousness: Implications for the Development of Antisocial Behavior | Study | 20 min (

The Science Behind Empathy and Empaths | Article | 5 min (

Study challenges perception that empathy erodes during medical school | Article | 5 min (


  • Mark Harris

    Rifkin’s book, The Empathic Civilization, is excellent.

    29 days ago
  • John

    Here is a link to an excellent article arguing against a myopic focus on empathy.

    23 days ago
  • John

    Here is a link to a free ebook that is entitled Compassion: Bridging Science and Practice. The book is the culmination of research findings in social neuroscience studies conducted by Tania Singer and others. There are multiple formats for download.

    23 days ago
  • John

    Here is a link to an article about Tania Singer’s research in Science Magazine.

    23 days ago
  • Edward

    From the link: “Patterns associated with empathic care, for instance, overlapped with systems in the brain associated with value and reward, such as the ventromedial prefrontal cortex and the medial orbitofrontal cortex. In contrast, patterns of empathic distress overlapped with systems in the brain known for mirroring, such as the premotor cortex and the primary and secondary somatosensory cortices, which help an individual simulate or imagine what another person is feeling or thinking.”

    23 days ago
  • Edward

    Here’s another one I just read: “Brain imaging reveals neural roots of caring.

    23 days ago
  • Edward

    From the conclusion: “Shared representations of affective states are activated from the top down in more  cognitive forms of empathy, which recruit additional executive and visuospatial processes. However, the literature overestimates distinctions between emotional and cognitive empathy, following traditional practices to dichotomize in science and philosophy. Despite each
    having unique features, affective and cognitive empathy both require access to the shared representations of emotion that provide simulations with content and an
    embodied meaning.”

    23 days ago
  • Edward

    The entire article can be read here:

    23 days ago
  • Edward

    And this article. Abstract: “Recent research on empathy in humans and other mammals seeks to dissociate emotional and cognitive empathy. These forms, however, remain interconnected in evolution, across species and at the level of neural mechanisms. New data have facilitated the development of empathy models such as the perception–action model (PAM) and mirror-neuron theories. According to the PAM, the emotional states of others are understood through personal, embodied representations that allow empathy and accuracy to increase based on the observer’s past experiences. In this Review, we discuss the latest evidence from studies carried out across a wide range of species, including studies on yawn contagion, consolation, aid-giving and contagious physiological affect, and we summarize neuroscientific data on representations related to another’s state.”

    23 days ago
  • John

    Here is a link to an excellent video of 4 researchers giving talks at the Stanford CCARE conference. The video is 75 minutes.
    CCARE Science of Compassion 2014: Introduction to the Science of Empathy, Altruism, and Compassion

    22 days ago
  • Edward

    Jimmy Kimmel in this video highlights a lot of what we talked about tonight. Yes, we need to feel empathy for those killed an injured in the Las Vegas shooting, but we also need to DO something about it. Meaning gun legislation. He highlights those in Congress who are making it easier instead of harder to obtain the kind of automatic weapons used in this mass murder. The reality is we must make such guns illegal, for it acts on our empathy and morality in a way that protects and serves us.

    21 days ago