Tag Archives: sex differences

‘Neurosexism’ debated

Neuroscientist Larry Cahill takes issue with a Feb 2019 Nature favorable book review of Gina Rippon’s The Gendered Brain: The New Neuroscience That Shatters The Myth Of The Female Brain.

Cahill’s response prompted an interview by Medium Neuroscience writer Meghan Daum.

Scientific findings have a way of upsetting apple carts, especially when we consider our oft-demonstrated human capacity to bend science to advantage some power-coveting groups over others.

Valid research amply shows there are real differences in male and female neuroanatomy and functions. Honest science must follow the evidence where it leads. Clearly, any discovered differences cannot be allowed to justify unequal social or economic opportunities or treatment. Cahill compares the situation to genetics. That people differ genetically in a vast number of ways cannot be taken as cause to misstate scientific findings or preclude further learning about genetics.

There are times and circumstances in which certain research approaches must be blocked for humane or other reasons but that is a different argument than denying the findings of a body of research because they are uncomfortable or inconvenient.

Thoughts?

Sex differences in the gut-microbiome-brain axis

Abstract

In recent years, the bidirectional communication between the gut microbiome and the brain has emerged as a factor that influences immunity, metabolism, neurodevelopment and behaviour. Cross-talk between the gut and brain begins early in life immediately following the transition from a sterile in utero environment to one that is exposed to a changing and complex microbial milieu over a lifetime. Once established, communication between the gut and brain integrates information from the autonomic and enteric nervous systems, neuroendocrine and neuroimmune signals, and peripheral immune and metabolic signals. Importantly, the composition and functional potential of the gut microbiome undergoes many transitions that parallel dynamic periods of brain development and maturation for which distinct sex differences have been identified. Here, we discuss the sexually dimorphic development, maturation and maintenance of the gut microbiome–brain axis, and the sex differences therein important in disease risk and resilience throughout the lifespan.

http://rstb.royalsocietypublishing.org/content/371/1688/20150122